MMORPG.com has a nice debate going on the subject, and I find myself siding with Dana, the Yes-You-Should guy: his responses are well thought through and insightful:
It is the responsibility of developers to pick IPs that has fans as excited about the worlds as the individual stories; which is to say appropriate worlds for development. Perpetual Entertainment’s choice of Star Trek has that potential. That franchise has existed and been popular in a number of incarnations. The only common thread is the universe in which the shows are set. Thus, I believe fans of the series will have no problem with the fact that they cannot be Captain Kirk.
Jon makes a number of points about how any deviations from the original story or world is an inevitable disappointment to the fans who live and breathe that world; he has a point, but this is surely unavoidable. It falls into the same category as the person who doesn't want to see Lord Of The Rings so as not to spoil the mental picture they have in their head from reading the book...?